About 9 results found for searched term "A-395" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11244 | A-395 | PRC2/EED |
| A-395 is A Polycomb inhibitory complex 2 (Polycomb repressive complex 2; PRC2), a protein-protein interaction antagonist, inhibits the trimer PRC2 complex (ezh2-EED -SUZ12) with an IC50 value of 18 nM. | ||
| M11403 | A939572 | Stearoyl-CoA Desaturase |
| A939572 is a potent, orally active stearyl CoA desaturase 1 SCD1 inhibitor that acts on mSCD1 and hSCD1 with IC50 <4 nM and 37 nM, respectively. | ||
| M21831 | AG-13958 | Others |
| AG-13958 | ||
| M10768 | SKF83959 | Others |
| SKF83959 is a potent selective dopamine D1-like Receptor partial agonist. SKF83959 Ki to rats D1，D5，D2AND D3 The values are 1.18, 7.56, 920, and 399 nM, respectively. SKF83959 is a potent sigma (σ)-1 receptor allosteric modulator. SKF83959 belongs to the benzazepine family and has an improving effect on cognitive dysfunction. SKF83959 can be used to study Alzheimer's disease and depression. | ||
| M14764 | RTI-13951-33 hydrochloride | Others |
| RTI-13951-33 hydrochloride is a potent, selective, and brain-penetrant GPR88 agonist, with an EC50 of 25 nM in GPR88 cAMP functional assay. RTI-13951-33 hydrochloride reduces alcohol reinforcement and intake behaviors in rats. | ||
| M20703 | JHU395 | Others |
| JHU395 is a novel orally bioavailable GA (glutamine antagonists) prodrug designed to circulate inert in plasma, but permeate and release active GA within target tissues. JHU395 delivers active GA to malignant peripheral nerve sheath tumor (MPNST), and significantly inhibits tumor growth without observed toxicity. | ||
| M29415 | RTI-13951-33 | GPR/FFAR |
| RTI-13951-33 is a potent, selective, and brain-penetrant GPR88 agonist, with an EC50 of 25 nM in GPR88 cAMP functional assay. RTI-13951-33 reduces alcohol reinforcement and intake behaviors in rats. | ||
| M30011 | Mibampator | GluR |
| LY451395 | ||
| Mibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors. | ||
| M30087 | Dehydro-ZINC39395747 | Others |
| Dehydro-ZINC39395747 is a derivative of ZINC39395747. ZINC39395747 is a potent cytochrome b5 reductase 3 (CYB5R3) inhibitor with an IC50 of 9.14 μM and a Kd of 1.11 μM. ZINC39395747 can increase NO bioavailability in vascular cells. | ||
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